Nuclear β-Catenin Is Increased in Systemic Sclerosis Pulmonary Fibrosis and Promotes Lung Fibroblast Migration and Proliferation

Pulmonary fibrosis is a disease that results in loss of normal lung architecture, but the signaling events that drive tissue destruction are incompletely understood. Wnt/β-catenin signaling is important in normal lung development, but whether abnormal signaling occurs in lung fibrosis due to systemi...

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Autors principals: Lam, Anna P., Flozak, Annette S., Russell, Susan, Wei, Jun, Jain, Manu, Mutlu, Gökhan M., Budinger, G. R.Scott, Feghali-Bostwick, Carol A., Varga, John, Gottardi, Cara J.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262680/
https://ncbi.nlm.nih.gov/pubmed/21454805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0113OC
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