β-catenin signaling: a novel mediator of fibrosis and potential therapeutic target

por Lam, Anna P., Gottardi, Cara J.
Publicado em 2011

Fat in Fibrosis

por Lam, Anna P., Gottardi, Cara J.
Publicado em 2013

Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells

por Lam, Anna P., Dean, David A.
Publicado em 2008

Multiple Cysts in the Kidney and Lungs in a Patient with Polycystic Kidney Disease and Lymphangioleiomyomatosis

por Lam, Anna P., Corbridge, Thomas C.
Publicado no ScientificWorldJournal (2007)

A Simple Method to Assess Abundance of the β-Catenin Signaling Pool in Cells

por Flozak, Annette S., Lam, Anna P., Gottardi, Cara J.
Publicado no Methods Mol Biol (2016)

Macrophages as a Source and Recipient of Wnt Signals

por Malsin, Elizabeth S., Kim, Seokjo, Lam, Anna P., Gottardi, Cara J.
Publicado no Front Immunol (2019)

Respiratory dysfunction following initiation of mirabegron: A case report

por Malsin, Elizabeth S., Coleman, John M., Wolfe, Lisa F., Lam, Anna P.
Publicado no Respir Med Case Rep (2019)

Adiponectin inhibits Lrp6 phosphorylation and β-catenin signaling

por Reinke, Lauren, Lam, Anna P., Flozak, Annette S., Varga, John, Gottardi, Cara J.
Publicado no Biochem Biophys Res Commun (2016)

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

por Wei, Jun, Fang, Feng, Lam, Anna P., Sargent, Jennifer L., Hamburg, Emily, Hinchcliff, Monique E., Gottardi, Cara J., Atit, Radhika, Whitfield, Michael L., Varga, John
Publicado em 2012

β-Catenin/T-cell Factor Signaling Is Activated during Lung Injury and Promotes the Survival and Migration of Alveolar Epithelial Cells

por Flozak, Annette S., Lam, Anna P., Russell, Susan, Jain, Manu, Peled, Ofra N., Sheppard, Kerry A., Beri, Rohinee, Mutlu, Gökhan M., Budinger, G. R. Scott, Gottardi, Cara J.
Publicado em 2010

Nuclear β-Catenin Is Increased in Systemic Sclerosis Pulmonary Fibrosis and Promotes Lung Fibroblast Migration and Proliferation

por Lam, Anna P., Flozak, Annette S., Russell, Susan, Wei, Jun, Jain, Manu, Mutlu, Gökhan M., Budinger, G. R.Scott, Feghali-Bostwick, Carol A., Varga, John, Gottardi, Cara J.
Publicado em 2011

Lrp5/β-Catenin Signaling Controls Lung Macrophage Differentiation and Inhibits Resolution of Fibrosis

por Sennello, Joseph A., Misharin, Alexander V., Flozak, Annette S., Berdnikovs, Sergejs, Cheresh, Paul, Varga, John, Kamp, David W., Budinger, G. R. Scott, Gottardi, Cara J., Lam, Anna P.
Publicado no Am J Respir Cell Mol Biol (2017)

Asbestos-Induced Alveolar Epithelial Cell Apoptosis. The Role of Endoplasmic Reticulum Stress Response

por Kamp, David W., Liu, Gang, Cheresh, Paul, Kim, Seok-Jo, Mueller, Amanda, Lam, Anna P, Trejo, Humberto, Williams, David, Tulasiram, Sandhya, Baker, Margaret, Ridge, Karen, Chandel, Navdeep S., Beri, Rohinee
Publicado em 2013

Wnt Coreceptor Lrp5 Is a Driver of Idiopathic Pulmonary Fibrosis

por Lam, Anna P., Herazo-Maya, Jose D., Sennello, Joseph A., Flozak, Annette S., Russell, Susan, Mutlu, Gökhan M., Budinger, G. R. Scott, DasGupta, Ramanuj, Varga, John, Kaminski, Naftali, Gottardi, Cara J.
Publicado no Am J Respir Crit Care Med (2014)

Utility of [(18)F]2-Fluoro-2-Deoxyglucose-PET in Sporadic and Tuberous Sclerosis-Associated Lymphangioleiomyomatosis

por Young, Lisa R., Franz, David N., Nagarkatte, Preeti, Fletcher, Christopher D. M., Wikenheiser-Brokamp, Kathryn A., Galsky, Matthew D., Corbridge, Thomas C., Lam, Anna P., Gelfand, Michael J., McCormack, Francis X.
Publicado em 2009

Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis

por Kim, Seok-Jo, Cheresh, Paul, Jablonski, Renea P., Rachek, Lyudmila, Yeldandi, Anjana, Piseaux-Aillon, Raul, Ciesielski, Mark J., Ridge, Karen, Gottardi, Cara, Lam, Anna P., Pardo, Annie, Selman, Moises, Natarajan, Viswanathan, Kamp, David W.
Publicado no Am J Physiol Lung Cell Mol Physiol (2020)

The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Pulmonary Fibrosis by Reducing Lung Epithelial Cell mtDNA Damage and Recruitment of Fibrogenic Monocytes

por Cheresh, Paul, Kim, Seok-Jo, Huang, Long Shuang, Watanabe, Satoshi, Joshi, Nikita, Williams, Kinola J.N., Chi, Monica, Lu, Ziyan, Harijith, Anantha, Yeldandi, Anjana, Lam, Anna P., Gottardi, Cara, Misharin, Alexander V., Budinger, G.R. Scott, Natarajan, Viswanathan, Kamp, David W.
Publicado no Int J Mol Sci (2020)

Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β(1) signalling

por Mutlu, Gökhan M, Budinger, G R Scott, Wu, Minghua, Lam, Anna P, Zirk, Aaron, Rivera, Stephanie, Urich, Daniela, Chiarella, Sergio E, Go, Leonard H T, Ghosh, Asish K, Selman, Moises, Pardo, Annie, Varga, John, Kamp, David W, Chandel, Navdeep S, Sznajder, Jacob Iasha, Jain, Manu
Publicado em 2011

Vimentin regulates activation of the NLRP3 inflammasome

por dos Santos, Gimena, Rogel, Micah R., Baker, Margaret A., Troken, James R., Urich, Daniela, Morales-Nebreda, Luisa, Sennello, Joseph A., Kutuzov, Mikhail A., Sitikov, Albert, Davis, Jennifer M., Lam, Anna P., Cheresh, Paul, Kamp, David, Shumaker, Dale K., Budinger, G. R. Scott, Ridge, Karen M.
Publicado no Nat Commun (2015)

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

por Misharin, Alexander V., Morales-Nebreda, Luisa, Reyfman, Paul A., Cuda, Carla M., Walter, James M., McQuattie-Pimentel, Alexandra C., Chen, Ching-I, Anekalla, Kishore R., Joshi, Nikita, Williams, Kinola J.N., Abdala-Valencia, Hiam, Yacoub, Tyrone J., Chi, Monica, Chiu, Stephen, Gonzalez-Gonzalez, Francisco J., Gates, Khalilah, Lam, Anna P., Nicholson, Trevor T., Homan, Philip J., Soberanes, Saul, Dominguez, Salina, Morgan, Vince K., Saber, Rana, Shaffer, Alexander, Hinchcliff, Monique, Marshall, Stacy A., Bharat, Ankit, Berdnikovs, Sergejs, Bhorade, Sangeeta M., Bartom, Elizabeth T., Morimoto, Richard I., Balch, William E., Sznajder, Jacob I., Chandel, Navdeep S., Mutlu, Gökhan M., Jain, Manu, Gottardi, Cara J., Singer, Benjamin D., Ridge, Karen M., Bagheri, Neda, Shilatifard, Ali, Budinger, G.R. Scott, Perlman, Harris
Publicado no J Exp Med (2017)