Wnt Coreceptor Lrp5 Is a Driver of Idiopathic Pulmonary Fibrosis

Rationale: Wnt/β-catenin signaling has been implicated in lung fibrosis, but how this occurs and whether expression changes in Wnt pathway components predict disease progression is unknown. Objectives: To determine whether the Wnt coreceptor Lrp5 drives pulmonary fibrosis in mice and is predictive o...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Lam, Anna P., Herazo-Maya, Jose D., Sennello, Joseph A., Flozak, Annette S., Russell, Susan, Mutlu, Gökhan M., Budinger, G. R. Scott, DasGupta, Ramanuj, Varga, John, Kaminski, Naftali, Gottardi, Cara J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226053/
https://ncbi.nlm.nih.gov/pubmed/24921217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201401-0079OC
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