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Dissecting Molecular Differences between Wnt Coreceptors LRP5 and LRP6

Low-density lipoprotein receptor-related proteins 5 and 6 (LRP5 and LRP6) serve as Wnt co-receptors for the canonical β-catenin pathway. While LRP6 is essential for embryogenesis, both LRP5 and LRP6 play critical roles for skeletal remodeling, osteoporosis pathogenesis and cancer formation, making L...

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Bibliografische gegevens
Hoofdauteurs: MacDonald, Bryan T., Semenov, Mikhail V., Huang, He, He, Xi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160902/
https://ncbi.nlm.nih.gov/pubmed/21887268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023537
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