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Frizzled and LRP5/6 Receptors for Wnt/β-Catenin Signaling

Frizzled and LRP5/6 are Wnt receptors that upon activation lead to stabilization of cytoplasmic β-catenin. In this study, we review the current knowledge of these two families of receptors, including their structures and interactions with Wnt proteins, and signaling mechanisms from receptor activati...

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Detalles Bibliográficos
Main Authors: MacDonald, Bryan T., He, Xi
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504444/
https://ncbi.nlm.nih.gov/pubmed/23209147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007880
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