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Frizzled and LRP5/6 Receptors for Wnt/β-Catenin Signaling
Frizzled and LRP5/6 are Wnt receptors that upon activation lead to stabilization of cytoplasmic β-catenin. In this study, we review the current knowledge of these two families of receptors, including their structures and interactions with Wnt proteins, and signaling mechanisms from receptor activati...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504444/ https://ncbi.nlm.nih.gov/pubmed/23209147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007880 |
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