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Inhibition of GSK3 Phosphorylation of β-Catenin via Phosphorylated PPPSPXS Motifs of Wnt Coreceptor LRP6

The Wnt/β-catenin signaling pathway plays essential roles in cell proliferation and differentiation, and deregulated β-catenin protein levels lead to many types of human cancers. On activation by Wnt, the Wnt co-receptor LDL receptor related protein 6 (LRP6) is phosphorylated at multiple conserved i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wu, Geng, Huang, He, Abreu, Jose Garcia, He, Xi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654145/
https://ncbi.nlm.nih.gov/pubmed/19293931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004926
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