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Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6
Many membrane proteins fold inefficiently and require the help of enzymes and chaperones. Here we reveal a novel folding assistance system that operates on membrane proteins from the cytosolic side of the endoplasmic reticulum (ER). We show that folding of the Wnt signaling coreceptor LRP6 is promot...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5102578/ https://ncbi.nlm.nih.gov/pubmed/27751231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19083 |
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