Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key proteins of the endoplasmic reticulum, is controlled by an upstream palmitoyltransferase, ZDHHC16,...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Abrami, Laurence, Dallavilla, Tiziano, Sandoz, Patrick A, Demir, Mustafa, Kunz, Béatrice, Savoglidis, Georgios, Hatzimanikatis, Vassily, van der Goot, F Gisou
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582869/
https://ncbi.nlm.nih.gov/pubmed/28826475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27826
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