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Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key proteins of the endoplasmic reticulum, is controlled by an upstream palmitoyltransferase, ZDHHC16,...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Abrami, Laurence, Dallavilla, Tiziano, Sandoz, Patrick A, Demir, Mustafa, Kunz, Béatrice, Savoglidis, Georgios, Hatzimanikatis, Vassily, van der Goot, F Gisou
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582869/
https://ncbi.nlm.nih.gov/pubmed/28826475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27826
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