The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling

Por Wei, Jun, Ghosh, Archit K., Chu, Haiyan, Fang, Feng, Hinchcliff, Monique E., Wang, Jiucun, Marangoni, Roberta Goncalves, Varga, John
Publicado no Arthritis Rheumatol (2015)

Longitudinal evaluation of PROMIS-29 and FACIT-Dyspnea short forms in systemic sclerosis

Por Hinchcliff, Monique E., Beaumont, Jennifer L, Carns, Mary A., Podlusky, Sofia, Thavarajah, Krishna, Varga, John, Cella, David, Chang, Rowland W
Publicado no J Rheumatol (2014)

Systems Level Analysis of Systemic Sclerosis Shows a Network of Immune and Profibrotic Pathways Connected with Genetic Polymorphisms

Por Mahoney, J. Matthew, Taroni, Jaclyn, Martyanov, Viktor, Wood, Tammara A., Greene, Casey S., Pioli, Patricia A., Hinchcliff, Monique E., Whitfield, Michael L.
Publicado no PLoS Comput Biol (2015)

Post-epidemic eosinophilia myalgia syndrome associated with L-Tryptophan

Por Allen, Jeffrey A, Peterson, Alicia, Sufit, Robert, Hinchcliff, Monique E, Mahoney, J. Matthew, Wood, Tammara A, Miller, Frederick W, Whitfield, Michael L, Varga, John
Publicado em 2011

Experimentally-Derived Fibroblast Gene Signatures Identify Molecular Pathways Associated with Distinct Subsets of Systemic Sclerosis Patients in Three Independent Cohorts

Por Johnson, Michael E., Mahoney, J. Matthew, Taroni, Jaclyn, Sargent, Jennifer L., Marmarelis, Eleni, Wu, Ming-Ru, Varga, John, Hinchcliff, Monique E., Whitfield, Michael L.
Publicado no PLoS One (2015)

The Pulmonary Fibrosis-Associated MUC5B Promoter Polymorphism Does Not Influence the Development of Interstitial Pneumonia in Systemic Sclerosis

Por Peljto, Anna L., Steele, Mark P., Fingerlin, Tasha E., Hinchcliff, Monique E., Murphy, Elissa, Podlusky, Sofia, Carns, Mary, Schwarz, Marvin, Varga, John, Schwartz, David A.
Publicado em 2012

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

Por Wei, Jun, Fang, Feng, Lam, Anna P., Sargent, Jennifer L., Hamburg, Emily, Hinchcliff, Monique E., Gottardi, Cara J., Atit, Radhika, Whitfield, Michael L., Varga, John
Publicado em 2012

Early Growth Response 3 (Egr-3) Is Induced by Transforming Growth Factor-β and Regulates Fibrogenic Responses

Por Fang, Feng, Shangguan, Anna J., Kelly, Kathleen, Wei, Jun, Gruner, Katherine, Ye, Boping, Wang, Wenxia, Bhattacharyya, Swati, Hinchcliff, Monique E., Tourtellotte, Warren G., Varga, John
Publicado em 2013

A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis

Por Taroni, Jaclyn N., Greene, Casey S., Martyanov, Viktor, Wood, Tammara A., Christmann, Romy B., Farber, Harrison W., Lafyatis, Robert A., Denton, Christopher P., Hinchcliff, Monique E., Pioli, Patricia A., Mahoney, J. Matthew, Whitfield, Michael L.
Publicado no Genome Med (2017)

Immunochip Analysis Identifies Multiple Susceptibility Loci for Systemic Sclerosis

Por Mayes, Maureen D., Bossini-Castillo, Lara, Gorlova, Olga, Martin, José Ezequiel, Zhou, Xiaodong, Chen, Wei V., Assassi, Shervin, Ying, Jun, Tan, Filemon K., Arnett, Frank C., Reveille, John D., Guerra, Sandra, Teruel, María, Carmona, Francisco David, Gregersen, Peter K., Lee, Annette T., López-Isac, Elena, Ochoa, Eguzkine, Carreira, Patricia, Simeón, Carmen Pilar, Castellví, Iván, González-Gay, Miguel Ángel, Zhernakova, Alexandra, Padyukov, Leonid, Alarcón-Riquelme, Marta, Wijmenga, Cisca, Brown, Matthew, Beretta, Lorenzo, Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Kreuter, Alexander, Distler, Jörg H.W., Voskuyl, Alexandre E., Schuerwegh, Annemie J., Hesselstrand, Roger, Nordin, Annika, Airó, Paolo, Lunardi, Claudio, Shiels, Paul, van Laar, Jacob M., Herrick, Ariane, Worthington, Jane, Denton, Christopher, Wigley, Fredrick M., Hummers, Laura K., Varga, John, Hinchcliff, Monique E., Baron, Murray, Hudson, Marie, Pope, Janet E., Furst, Daniel E., Khanna, Dinesh, Phillips, Kristin, Schiopu, Elena, Segal, Barbara M., Molitor, Jerry A., Silver, Richard M., Steen, Virginia D., Simms, Robert W., Lafyatis, Robert A., Fessler, Barri J., Frech, Tracy M., AlKassab, Firas, Docherty, Peter, Kaminska, Elzbieta, Khalidi, Nader, Jones, Henry Niall, Markland, Janet, Robinson, David, Broen, Jasper, Radstake, Timothy R.D.J., Fonseca, Carmen, Koeleman, Bobby P., Martin, Javier
Publicado em 2014