A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a multi-organ autoimmune disease characterized by skin fibrosis. Internal organ involvement is heterogeneous. It is unknown whether disease mechanisms are common across all involved affected tissues or if each manifestation has a distinct underlying pathology....

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Détails bibliographiques
Publié dans:Genome Med
Auteurs principaux: Taroni, Jaclyn N., Greene, Casey S., Martyanov, Viktor, Wood, Tammara A., Christmann, Romy B., Farber, Harrison W., Lafyatis, Robert A., Denton, Christopher P., Hinchcliff, Monique E., Pioli, Patricia A., Mahoney, J. Matthew, Whitfield, Michael L.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363043/
https://ncbi.nlm.nih.gov/pubmed/28330499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0417-1
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