A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a multi-organ autoimmune disease characterized by skin fibrosis. Internal organ involvement is heterogeneous. It is unknown whether disease mechanisms are common across all involved affected tissues or if each manifestation has a distinct underlying pathology....

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Taroni, Jaclyn N., Greene, Casey S., Martyanov, Viktor, Wood, Tammara A., Christmann, Romy B., Farber, Harrison W., Lafyatis, Robert A., Denton, Christopher P., Hinchcliff, Monique E., Pioli, Patricia A., Mahoney, J. Matthew, Whitfield, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363043/
https://ncbi.nlm.nih.gov/pubmed/28330499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0417-1
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