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A Functional Genomic Meta-Analysis of Clinical Trials in Systemic Sclerosis: Toward Precision Medicine and Combination Therapy

Systemic sclerosis is an orphan, systemic autoimmune disease with no FDA-approved treatments. Its heterogeneity and rarity often result in underpowered clinical trials making the analysis and interpretation of associated molecular data challenging. We performed a meta-analysis of gene expression dat...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: Taroni, Jaclyn N., Martyanov, Viktor, Mahoney, J. Matthew, Whitfield, Michael L.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190797/
https://ncbi.nlm.nih.gov/pubmed/28011145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.12.007
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