The Pulmonary Fibrosis-Associated MUC5B Promoter Polymorphism Does Not Influence the Development of Interstitial Pneumonia in Systemic Sclerosis

BACKGROUND: More than 80% of patients with systemic sclerosis (SSc) develop lung involvement, most commonly interstitial pneumonia (IP). We recently identified a common variant in the promoter region of MUC5B (rs35705950) that has a significant effect on the risk of developing both familial and spor...

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Autori principali: Peljto, Anna L., Steele, Mark P., Fingerlin, Tasha E., Hinchcliff, Monique E., Murphy, Elissa, Podlusky, Sofia, Carns, Mary, Schwarz, Marvin, Varga, John, Schwartz, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American College of Chest Physicians 2012
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515031/
https://ncbi.nlm.nih.gov/pubmed/22576636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.12-0110
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