MUC5B Promoter Polymorphism and Interstitial Lung Abnormalities

BACKGROUND: A common promoter polymorphism (rs35705950) in MUC5B, the gene encoding mucin 5B, is associated with idiopathic pulmonary fibrosis. It is not known whether this polymorphism is associated with interstitial lung disease in the general population. METHODS: We performed a blinded assessment...

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Detalhes bibliográficos
Main Authors: Hunninghake, Gary M., Hatabu, Hiroto, Okajima, Yuka, Gao, Wei, Dupuis, Josée, Latourelle, Jeanne C., Nishino, Mizuki, Araki, Tetsuro, Zazueta, Oscar E., Kurugol, Sila, Ross, James C., Estépar, Raúl San José, Murphy, Elissa, Steele, Mark P., Loyd, James E., Schwarz, Marvin I., Fingerlin, Tasha E., Rosas, Ivan O., Washko, George R., O’Connor, George T., Schwartz, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747636/
https://ncbi.nlm.nih.gov/pubmed/23692170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1216076
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