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Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells

BACKGROUND: We have shown previously that cyclic stretch corresponding to that experienced by the pulmonary epithelium during normal breathing enhances nonviral gene transfer and expression in alveolar epithelial cells by increasing plasmid intracellular trafficking. Although reorganization of the m...

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Autors principals: Lam, Anna P., Dean, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084625/
https://ncbi.nlm.nih.gov/pubmed/18361478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1187
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