Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment

por Rosencrance, Celeste D., Ammouri, Haneen N., Yu, Qi, Ge, Tiffany, Rendleman, Emily J., Marshall, Stacy A., Eagen, Kyle P.
Publicado en Mol Cell (2020)

PAF1, a molecular regulator of promoter-proximal pausing by RNA Polymerase II

por Chen, Fei, Woodfin, Ashley R., Gardini, Alessandro, Rickels, Ryan A., Marshall, Stacy A., Smith, Edwin R., Shiekhattar, Ramin, Shilatifard, Ali
Publicado en Cell (2015)

An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells

por Cao, Kaixiang, Collings, Clayton K., Morgan, Marc A., Marshall, Stacy A., Rendleman, Emily J., Ozark, Patrick A., Smith, Edwin R., Shilatifard, Ali
Publicado en Sci Adv (2018)

NELF regulates a promoter-proximal step distinct from RNA Pol II pause-release

por Aoi, Yuki, Smith, Edwin R., Shah, Avani P., Rendleman, Emily J., Marshall, Stacy A., Woodfin, Ashley R., Chen, Fei X., Shiekhattar, Ramin, Shilatifard, Ali
Publicado en Mol Cell (2020)

SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression

por Cao, Kaixiang, Collings, Clayton K., Marshall, Stacy A., Morgan, Marc A., Rendleman, Emily J., Wang, Lu, Sze, Christie C., Sun, Tianjiao, Bartom, Elizabeth T., Shilatifard, Ali
Publicado en Genes Dev (2017)

Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation

por Sze, Christie C., Cao, Kaixiang, Collings, Clayton K., Marshall, Stacy A., Rendleman, Emily J., Ozark, Patrick A., Chen, Fei Xavier, Morgan, Marc A., Wang, Lu, Shilatifard, Ali
Publicado en Genes Dev (2017)

A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism

por Wang, Lu, Collings, Clayton K., Zhao, Zibo, Cozzolino, Kira Alia, Ma, Quanhong, Liang, Kaiwei, Marshall, Stacy A., Sze, Christie C., Hashizume, Rintaro, Savas, Jeffrey Nicholas, Shilatifard, Ali
Publicado en Genes Dev (2017)

DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation

por Cao, Kaixiang, Ugarenko, Michal, Ozark, Patrick A., Wang, Juan, Marshall, Stacy A., Rendleman, Emily J., Liang, Kaiwei, Wang, Lu, Zou, Lihua, Smith, Edwin R., Yue, Feng, Shilatifard, Ali
Publicado en Proc Natl Acad Sci U S A (2020)

Coordinated regulation of cellular identity–associated H3K4me3 breadth by the COMPASS family

por Sze, Christie C., Ozark, Patrick A., Cao, Kaixiang, Ugarenko, Michal, Das, Siddhartha, Wang, Lu, Marshall, Stacy A., Rendleman, Emily J., Ryan, Caila A., Zha, Didi, Douillet, Delphine, Chen, Fei Xavier, Shilatifard, Ali
Publicado en Sci Adv (2020)

Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia

por Zhao, Zibo, Wang, Lu, Volk, Andrew G., Birch, Noah W., Stoltz, Kristen L., Bartom, Elizabeth T., Marshall, Stacy A., Rendleman, Emily J., Nestler, Carson M., Shilati, Joseph, Schiltz, Gary E., Crispino, John D., Shilatifard, Ali
Publicado en Genes Dev (2019)

PAF1 Regulation of Promoter-Proximal Pause Release via Enhancer Activation

por Chen, Fei Xavier, Xie, Peng, Collings, Clayton K, Cao, Kaixiang, Aoi, Yuki, Marshall, Stacy A., Rendleman, Emily J., Ugarenko, Michal, Ozark, Patrick A., Zhang, Anda, Shiekhattar, Ramin, Smith, Edwin R., Zhang, Michael Q., Shilatifard, Ali
Publicado en Science (2017)

TET2 coactivates gene expression through demethylation of enhancers

por Wang, Lu, Ozark, Patrick A., Smith, Edwin R., Zhao, Zibo, Marshall, Stacy A., Rendleman, Emily J., Piunti, Andrea, Ryan, Caila, Whelan, Anna L., Helmin, Kathryn A., Morgan, Marc Alard, Zou, Lihua, Singer, Benjamin D., Shilatifard, Ali
Publicado en Sci Adv (2018)

Targeting Processive Transcription Elongation Via SEC Disruption for Myc Induced Cancer Therapy

por Liang, Kaiwei, Smith, Edwin R., Aoi, Yuki, Stoltz, Kristen L., Katagi, Hiroaki, Woodfin, Ashley R., Rendleman, Emily J., Marshall, Stacy A., Murray, David C., Wang, Lu, Ozark, Patrick A., Mishra, Rama K., Hashizume, Rintaro, Schiltz, Gary E., Shilatifard, Ali
Publicado en Cell (2018)

Therapeutic targeting of MLL degradation pathways in MLL-rearranged leukemia

por Liang, Kaiwei, Volk1, Andrew G., Haug, Jeffrey S., Marshall, Stacy A., Woodfin, Ashley R., Bartom, Elizabeth T., Gilmore, Joshua M., Florens, Laurence, Washburn, Michael P., Sullivan, Kelly D., Espinosa, Joaquin M., Cannova, Joseph, Zhang, Jiwang, Smith, Edwin R., Crispino, John D., Shilatifard, Ali
Publicado en Cell (2017)

A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation

por Morgan, Marc A.J., Rickels, Ryan A., Collings, Clayton K., He, Xiaolin, Cao, Kaixiang, Herz, Hans-Martin, Cozzolino, Kira A., Abshiru, Nebiyu A., Marshall, Stacy A., Rendleman, Emily J., Sze, Christie C., Piunti, Andrea, Kelleher, Neil L., Savas, Jeffrey N., Shilatifard, Ali
Publicado en Genes Dev (2017)

Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb, and DNA methylation

por Douillet, Delphine, Sze, Christie C, Ryan, Caila, Piunti, Andrea, Shah, Avani P, Ugarenko, Michal, Marshall, Stacy A, Rendleman, Emily J, Zha, Didi, Helmin, Kathryn A, Zhao, Zibo, Cao, Kaixiang, Morgan, Marc A, Singer, Benjamin D, Bartom, Elizabeth, Smith, Edwin R, Shilatifard, Ali
Publicado en Nat Genet (2020)

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability

por Rickels, Ryan, Herz, Hans-Martin, Sze, Christie C, Cao, Kaixiang, Morgan, Marc A, Collings, Clayton K, Gause, Maria, Takahashi, Yoh-hei, Wang, Lu, Rendleman, Emily J, Marshall, Stacy A, Krueger, Annika, Bartom, Elizabeth T, Piunti, Andrea, Smith, Edwin, Abshiru, Nebiyu A, Kelleher, Neil L, Dorsett, Dale, Shilatifard, Ali
Publicado en Nat Genet (2017)

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

por Piunti, Andrea, Hashizume, Rintaro, Morgan, Marc A., Bartom, Elizabeth T., Horbinski, Craig M., Marshall, Stacy A., Rendleman, Emily J., Ma, Quanhong, Takahashi, Yoh-hei, Woodfin, Ashley R., Misharin, Alexander V., Abshiru, Nebiyu A., Lulla, Rishi R., Saratsis, Amanda M., Kelleher, Neil L., James, C. David, Shilatifard, Ali
Publicado en Nat Med (2017)

Resetting the Epigenetic Balance of Polycomb and COMPASS Function at Enhancers for Cancer Therapy

por Wang, Lu, Zhao, Zibo, Ozark, Patrick Alexander, Fantini, Damiano, Marshall, Stacy A., Rendleman, Emily J., Cozzolino, Kira A., Louis, Nundia, He, Xingyao, Morgan, Marc A., Takahashi, Yoh-hei, Collings, Clayton K., Smith, Edwin R., Ntziachristos, Panagiotis, Savas, Jeffrey N., Zou, Lihua, Hashizume, Rintaro, Meeks, Joshua J., Shilatifard, Ali
Publicado en Nat Med (2018)

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

por Misharin, Alexander V., Morales-Nebreda, Luisa, Reyfman, Paul A., Cuda, Carla M., Walter, James M., McQuattie-Pimentel, Alexandra C., Chen, Ching-I, Anekalla, Kishore R., Joshi, Nikita, Williams, Kinola J.N., Abdala-Valencia, Hiam, Yacoub, Tyrone J., Chi, Monica, Chiu, Stephen, Gonzalez-Gonzalez, Francisco J., Gates, Khalilah, Lam, Anna P., Nicholson, Trevor T., Homan, Philip J., Soberanes, Saul, Dominguez, Salina, Morgan, Vince K., Saber, Rana, Shaffer, Alexander, Hinchcliff, Monique, Marshall, Stacy A., Bharat, Ankit, Berdnikovs, Sergejs, Bhorade, Sangeeta M., Bartom, Elizabeth T., Morimoto, Richard I., Balch, William E., Sznajder, Jacob I., Chandel, Navdeep S., Mutlu, Gökhan M., Jain, Manu, Gottardi, Cara J., Singer, Benjamin D., Ridge, Karen M., Bagheri, Neda, Shilatifard, Ali, Budinger, G.R. Scott, Perlman, Harris
Publicado en J Exp Med (2017)