PAF1, a molecular regulator of promoter-proximal pausing by RNA Polymerase II

The control of promoter-proximal pausing and the release of RNA polymerase II (Pol II) is a widely used mechanism for regulating gene expression in metazoans, especially for genes that respond to environmental and developmental cues. Here, we identify Pol II-associated Factor 1 (PAF1) to possess an...

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Udgivet i:Cell
Main Authors: Chen, Fei, Woodfin, Ashley R., Gardini, Alessandro, Rickels, Ryan A., Marshall, Stacy A., Smith, Edwin R., Shiekhattar, Ramin, Shilatifard, Ali
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679144/
https://ncbi.nlm.nih.gov/pubmed/26279188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.042
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