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TFIID enables RNA polymerase II promoter-proximal pausing

RNA polymerase II (RNAPII) transcription is governed by the Pre-Initiation Complex (PIC), which contains TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, RNAPII, and Mediator. After initiation, RNAPII enzymes pause after transcribing less than 100 bases; precisely how RNAPII pausing is enforced and regulat...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Fant, CB, Levandowski, CB, Gupta, K, Maas, ZL, Moir, J, Rubin, JD, Sawyer, A, Esbin, MN, Rimel, JK, Luyties, O, Marr, MT, Berger, I, Dowell, RD, Taatjes, DJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245555/
https://ncbi.nlm.nih.gov/pubmed/32229306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.008
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