A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation

Histone H3 Lys4 (H3K4) methylation is a chromatin feature enriched at gene cis-regulatory sequences such as promoters and enhancers. Here we identify an evolutionarily conserved factor, BRWD2/PHIP, which colocalizes with histone H3K4 methylation genome-wide in human cells, mouse embryonic stem cells...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Morgan, Marc A.J., Rickels, Ryan A., Collings, Clayton K., He, Xiaolin, Cao, Kaixiang, Herz, Hans-Martin, Cozzolino, Kira A., Abshiru, Nebiyu A., Marshall, Stacy A., Rendleman, Emily J., Sze, Christie C., Piunti, Andrea, Kelleher, Neil L., Savas, Jeffrey N., Shilatifard, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710144/
https://ncbi.nlm.nih.gov/pubmed/29089422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.305201.117
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