An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements implemented by Trx/MLL/COMPASS

Polycomb Response Elements (PREs) are specific DNA sequences that stably maintain the developmental pattern of gene expression. Drosophila PREs are well characterized, whereas the existence of PREs in mammals remains debated. Accumulating evidence supports a model in which CGIs recruit Polycomb-Grou...

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Gepubliceerd in:Mol Cell
Hoofdauteurs: Rickels, Ryan, Hu, Deqing, Collings, Clayton K., Woodfin, Ashley R., Piunti, Andrea, Mohan, Man, Herz, Hans-Martin, Kvon, Evgeny, Shilatifard, Ali
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996622/
https://ncbi.nlm.nih.gov/pubmed/27447986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.06.018
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