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2027 The role of lysyl oxidase in systemic sclerosis-associated lung fibrosis

OBJECTIVES/SPECIFIC AIMS: Systemic sclerosis (SSc) is a connective tissue disease of unknown etiology characterized by progressive fibrosis of the skin and multiple visceral organs. Effective therapies for SSc are needed. Lysyl oxidase (LOX) is a copper-dependent amide oxidase that plays a critical...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Nguyen, Xinh-Xinh, Nishimoto, Tetsuya, Takihara, Takahisa, Mlakar, Logan, Riemer, Ellen, Heywood, Jonathan, Bradshaw, Amy, Feghali-Bostwick, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799236/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.138
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