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Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis
The murine bleomycin (BLM)-induced fibrosis model is the most widely used in systemic sclerosis (SSc) studies. It has been reported that systemic delivery of BLM via continuous diffusion from subcutaneously implanted osmotic minipumps can cause fibrosis of the skin, lungs, and other internal organs....
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484495/ https://ncbi.nlm.nih.gov/pubmed/28651005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179917 |
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