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An endostatin-derived peptide orally exerts anti-fibrotic activity in a murine pulmonary fibrosis model

OBJECTIVE: Pulmonary fibrosis causes high morbidity and mortality in affected individuals. Recently, we showed that parenteral or intratracheal administration of a peptide derived from endostatin, called E4, prevents and ameliorates fibrosis using different models of dermal and pulmonary disease. No...

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Bibliographische Detailangaben
Veröffentlicht in:Int Immunopharmacol
Hauptverfasser: Nishimoto, Tetsuya, Mlakar, Logan, Takihara, Takahisa, Feghali-Bostwick, Carol
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482421/
https://ncbi.nlm.nih.gov/pubmed/26315492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2015.07.039
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