Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis

Pulmonary fibrosis is one of the important causes of morbidity and mortality in fibroproliferative disorders such as systemic sclerosis (SSc) and idiopathic pulmonary fibrosis (IPF). Lysyl oxidase (LOX) is a copper-dependent amine oxidase whose primary function is the covalent crosslinking of collag...

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Publicado en:Am J Physiol Lung Cell Mol Physiol
Autores principales: Nguyen, Xinh-Xinh, Nishimoto, Tetsuya, Takihara, Takahisa, Mlakar, Logan, Bradshaw, Amy D., Feghali-Bostwick, Carol
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2021
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847064/
https://ncbi.nlm.nih.gov/pubmed/33026236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00173.2020
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