Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis

Pulmonary fibrosis is one of the important causes of morbidity and mortality in fibroproliferative disorders such as systemic sclerosis (SSc) and idiopathic pulmonary fibrosis (IPF). Lysyl oxidase (LOX) is a copper-dependent amine oxidase whose primary function is the covalent crosslinking of collag...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Nguyen, Xinh-Xinh, Nishimoto, Tetsuya, Takihara, Takahisa, Mlakar, Logan, Bradshaw, Amy D., Feghali-Bostwick, Carol
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847064/
https://ncbi.nlm.nih.gov/pubmed/33026236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00173.2020
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