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Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis

Pulmonary fibrosis is one of the important causes of morbidity and mortality in fibroproliferative disorders such as systemic sclerosis (SSc) and idiopathic pulmonary fibrosis (IPF). Lysyl oxidase (LOX) is a copper-dependent amine oxidase whose primary function is the covalent crosslinking of collag...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Nguyen, Xinh-Xinh, Nishimoto, Tetsuya, Takihara, Takahisa, Mlakar, Logan, Bradshaw, Amy D., Feghali-Bostwick, Carol
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847064/
https://ncbi.nlm.nih.gov/pubmed/33026236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00173.2020
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