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Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis

Pulmonary fibrosis is one of the important causes of morbidity and mortality in fibroproliferative disorders such as systemic sclerosis (SSc) and idiopathic pulmonary fibrosis (IPF). Lysyl oxidase (LOX) is a copper-dependent amine oxidase whose primary function is the covalent crosslinking of collag...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Nguyen, Xinh-Xinh, Nishimoto, Tetsuya, Takihara, Takahisa, Mlakar, Logan, Bradshaw, Amy D., Feghali-Bostwick, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847064/
https://ncbi.nlm.nih.gov/pubmed/33026236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00173.2020
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