Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis

The murine bleomycin (BLM)-induced fibrosis model is the most widely used in systemic sclerosis (SSc) studies. It has been reported that systemic delivery of BLM via continuous diffusion from subcutaneously implanted osmotic minipumps can cause fibrosis of the skin, lungs, and other internal organs....

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Watanabe, Tomoya, Nishimoto, Tetsuya, Mlakar, Logan, Heywood, Jonathan, Malaab, Maya, Hoffman, Stanley, Feghali-Bostwick, Carol
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484495/
https://ncbi.nlm.nih.gov/pubmed/28651005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179917
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