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Insulin‐like growth factor binding protein‐4 exerts antifibrotic activity by reducing levels of connective tissue growth factor and the C‐X‐C chemokine receptor 4

The insulin‐like growth factor (IGF) system plays an important role in variety cellular biological functions; we previously reported levels of IGF binding proteins (IGFBP)‐3 and ‐5 are increased in dermal and pulmonary fibrosis associated with the prototypic fibrosing disease systemic sclerosis (SSc...

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Detalhes bibliográficos
Publicado no:FASEB Bioadv
Main Authors: Su, YunYun, Nishimoto, Tetsuya, Hoffman, Stanley, Nguyen, Xinh‐Xinh, Pilewski, Joseph M., Feghali‐Bostwick, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720120/
https://ncbi.nlm.nih.gov/pubmed/31482149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2018-00015
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