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Localized Expression of Tenascin in Systemic Sclerosis-Associated Lung Fibrosis and its Regulation by IGF Binding Protein (IGFBP)-3

OBJECTIVE: Tenascin (TN)-C is an extracellular matrix protein associated with injury and remodeling. Since Transforming Growth Factor (TGF)-β induces both TN-C and Insulin-Like Growth Factor Binding Protein (IGFBP)-3, we sought to determine the role of IGFBP-3 in mediating TGF-β’s effects on TN-C pr...

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Main Authors: Brissett, Monique, Veraldi, Kristen L., Pilewski, Joseph M., Medsger, Thomas A., Feghali-Bostwick, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241902/
https://ncbi.nlm.nih.gov/pubmed/21898349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30647
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