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Insulin-Like Growth Factor Binding Proteins-3 and -5: Central Mediators of Fibrosis and Promising New Therapeutic Targets

Fibrosis involves an orchestrated cascade of events including activation of fibroblasts, increased production and deposition of extracellular matrix components, and differentiation of fibroblasts into myofibroblasts. Epithelial-mesenchymal cross-talk plays an important role in this process, and curr...

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Detalhes bibliográficos
Main Authors: Veraldi, Kristen L, Feghali-Bostwick, Carol A
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395973/
https://ncbi.nlm.nih.gov/pubmed/22802912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874312901206010140
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