Emerging concepts in intestinal immune control of obesity-related metabolic disease

per Khan, Saad, Luck, Helen, Winer, Shawn, Winer, Daniel A.
Publicat a Nat Commun (2021)

The Immune Landscape of Visceral Adipose Tissue During Obesity and Aging

per Khan, Saad, Chan, Yi Tao, Revelo, Xavier S., Winer, Daniel A.
Publicat a Front Endocrinol (Lausanne) (2020)

Immunologic impact of the intestine in metabolic disease

per Winer, Daniel A., Winer, Shawn, Dranse, Helen J., Lam, Tony K.T.
Publicat a J Clin Invest (2017)

B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance

per Winer, Daniel A., Winer, Shawn, Chng, Melissa H. Y., Shen, Lei, Engleman, Edgar G.
Publicat 2013

B-1a Lymphocytes Attenuate Insulin Resistance

per Shen, Lei, Chng, MH, Alonso, Michael N., Yuan, Robert, Winer, Daniel A., Engleman, Edgar G.
Publicat a Diabetes (2015)

FAK signalling controls insulin sensitivity through regulation of adipocyte survival

per Luk, Cynthia T., Shi, Sally Yu, Cai, Erica P., Sivasubramaniyam, Tharini, Krishnamurthy, Mansa, Brunt, Jara J., Schroer, Stephanie A., Winer, Daniel A., Woo, Minna
Publicat a Nat Commun (2017)

An immunosuppressive dendritic cell subset accumulates at secondary sites and promotes metastasis in pancreatic cancer

per Kenkel, Justin A., Tseng, William W., Davidson, Matthew G., Tolentino, Lorna L., Choi, Okmi, Bhattacharya, Nupur, Seeley, E. Scott, Winer, Daniel A., Reticker-Flynn, Nathan E., Engleman, Edgar G.
Publicat a Cancer Res (2017)

The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis

per Soares, Fraser, Tattoli, Ivan, Rahman, Muhammed A., Robertson, Susan J., Belcheva, Antoaneta, Liu, Daniel, Streutker, Catherine, Winer, Shawn, Winer, Daniel A., Martin, Alberto, Philpott, Dana J., Arnoult, Damien, Girardin, Stephen E.
Publicat 2014

Human Regulatory Dendritic Cells Develop From Monocytes in Response to Signals From Regulatory and Helper T Cells

per Zhang, Xiangyue, Zheng, Pingping, Prestwood, Tyler R., Zhang, Hong, Carmi, Yaron, Tolentino, Lorna L., Wu, Nancy, Choi, Okmi, Winer, Daniel A., Strober, Samuel, Kang, Eun-Suk, Alonso, Michael N., Engleman, Edgar G.
Publicat a Front Immunol (2020)

Aryl hydrocarbon receptor agonist indigo protects against obesity-related insulin resistance through modulation of intestinal and metabolic tissue immunity

per Lin, Yi-Hsuan, Luck, Helen, Khan, Saad, Schneeberger, Pierre H. H., Tsai, Sue, Clemente-Casares, Xavier, Lei, Helena, Leu, Yann-Lii, Chan, Yi Tao, Chen, Hsing-Yu, Yang, Sien-Hung, Coburn, Bryan, Winer, Shawn, Winer, Daniel A.
Publicat a Int J Obes (Lond) (2019)

DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice

per Shi, Sally Yu, Lu, Shun-Yan, Sivasubramaniyam, Tharini, Revelo, Xavier S., Cai, Erica P., Luk, Cynthia T., Schroer, Stephanie A., Patel, Prital, Kim, Raymond H., Bombardier, Eric, Quadrilatero, Joe, Tupling, A. Russell, Mak, Tak W., Winer, Daniel A., Woo, Minna
Publicat a Nat Commun (2015)

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

per Desai, Harsh R., Sivasubramaniyam, Tharini, Revelo, Xavier S., Schroer, Stephanie A., Luk, Cynthia T., Rikkala, Prashanth R., Metherel, Adam H., Dodington, David W., Park, Yoo Jin, Kim, Min Jeong, Rapps, Joshua A., Besla, Rickvinder, Robbins, Clinton S., Wagner, Kay-Uwe, Bazinet, Richard P., Winer, Daniel A., Woo, Minna
Publicat a Sci Rep (2017)

B Lymphocytes Promote Insulin Resistance through Modulation of T Lymphocytes and Production of Pathogenic IgG Antibody

per Winer, Daniel A., Winer, Shawn, Shen, Lei, Wadia, Persis P., Yantha, Jason, Paltser, Geoffrey, Tsui, Hubert, Wu, Ping, Davidson, Matthew G., Alonso, Michael N., Leong, Hweixian, Glassford, Alec, Caimol, Maria, Kenkel, Justin A., Tedder, Thomas F., McLaughlin, Tracey, Miklos, David B, Dosch, H.-Michael, Engleman, Edgar G.
Publicat 2011

Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages

per Sivasubramaniyam, Tharini, Yang, Jiaqi, Cheng, Henry S., Zyla, Alexandra, Li, Angela, Besla, Rickvinder, Dotan, Idit, Revelo, Xavier S., Shi, Sally Yu, Le, Helen, Schroer, Stephanie A., Dodington, David W., Park, Yoo Jin, Kim, Min Jeong, Febbraro, Daniella, Ruel, Isabelle, Genest, Jacques, Kim, Raymond H., Mak, Tak W., Winer, Daniel A., Robbins, Clinton S., Woo, Minna
Publicat a Sci Rep (2021)

Type I Interferon Responses Drive Intrahepatic T cells to Promote Metabolic Syndrome

per Ghazarian, Magar, Revelo, Xavier S., Nøhr, Mark K., Luck, Helen, Zeng, Kejing, Lei, Helena, Tsai, Sue, Schroer, Stephanie A., Park, Yoo Jin, Chng, Melissa Hui Yen, Shen, Lei, D’Angelo, June Ann, Horton, Peter, Chapman, William C., Brockmeier, Diane, Woo, Minna, Engleman, Edgar G., Adeyi, Oyedele, Hirano, Naoto, Jin, Tianru, Gehring, Adam J., Winer, Shawn, Winer, Daniel A.
Publicat a Sci Immunol (2017)

NUCLEIC ACID TARGETING PATHWAYS PROMOTE INFLAMMATION IN OBESITY RELATED INSULIN RESISTANCE

per Revelo, Xavier S., Ghazarian, Magar, Chng, Melissa Hui Yen, Luck, Helen, Kim, Justin H., Zeng, Kejing, Shi, Sally Y., Tsai, Sue, Lei, Helena, Kenkel, Justin, Liu, Chih Long, Tangsombatvisit, Stephanie, Tsui, Hubert, Sima, Corneliu, Xiao, Changting, Shen, Lei, Li, Xiaoying, Jin, Tianru, Lewis, Gary F., Woo, Minna, Utz, Paul J., Glogauer, Michael, Engleman, Edgar, Winer, Shawn, Winer, Daniel A.
Publicat a Cell Rep (2016)

Gut-associated IgA(+) immune cells regulate obesity-related insulin resistance

per Luck, Helen, Khan, Saad, Kim, Justin H., Copeland, Julia K., Revelo, Xavier S., Tsai, Sue, Chakraborty, Mainak, Cheng, Kathleen, Tao Chan, Yi, Nøhr, Mark K., Clemente-Casares, Xavier, Perry, Marie-Christine, Ghazarian, Magar, Lei, Helena, Lin, Yi-Hsuan, Coburn, Bryan, Okrainec, Allan, Jackson, Timothy, Poutanen, Susan, Gaisano, Herbert, Allard, Johane P., Guttman, David S., Conner, Margaret E., Winer, Shawn, Winer, Daniel A.
Publicat a Nat Commun (2019)

Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10

per Rojas, Olga L., Pröbstel, Anne-Katrin, Porfilio, Elisa A., Wang, Angela A., Charabati, Marc, Sun, Tian, Lee, Dennis S.W., Galicia, Georgina, Ramaglia, Valeria, Ward, Lesley A., Leung, Leslie Y.T., Najafi, Ghazal, Khaleghi, Khashayar, Garcillán, Beatriz, Li, Angela, Besla, Rickvinder, Naouar, Ikbel, Cao, Eric Y., Chiaranunt, Pailin, Burrows, Kyle, Robinson, Hannah G., Allanach, Jessica R., Yam, Jennifer, Luck, Helen, Campbell, Daniel J., Allman, David, Brooks, David G., Tomura, Michio, Baumann, Ryan, Zamvil, Scott S., Bar-Or, Amit, Horwitz, Marc S., Winer, Daniel A., Mortha, Arthur, Mackay, Fabienne, Prat, Alexandre, Osborne, Lisa C., Robbins, Clinton, Baranzini, Sergio E., Gommerman, Jennifer L.
Publicat a Cell (2019)

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

per Agrawal, Nishant, Akbani, Rehan, Aksoy, B. Arman, Ally, Adrian, Arachchi, Harindra, Asa, Sylvia L., Auman, J. Todd, Balasundaram, Miruna, Balu, Saianand, Baylin, Stephen B., Behera, Madhusmita, Bernard, Brady, Beroukhim, Rameen, Bishop, Justin A., Black, Aaron D., Bodenheimer, Tom, Boice, Lori, Bootwalla, Moiz S., Bowen, Jay, Bowlby, Reanne, Bristow, Christopher A., Brookens, Robin, Brooks, Denise, Bryant, Robert, Buda, Elizabeth, Butterfield, Yaron S.N., Carling, Tobias, Carlsen, Rebecca, Carter, Scott L., Carty, Sally E., Chan, Timothy A., Chen, Amy Y., Cherniack, Andrew D., Cheung, Dorothy, Chin, Lynda, Cho, Juok, Chu, Andy, Chuah, Eric, Cibulskis, Kristian, Ciriello, Giovanni, Clarke, Amanda, Clayman, Gary L., Cope, Leslie, Copland, John, Covington, Kyle, Danilova, Ludmila, Davidsen, Tanja, Demchok, John A., DiCara, Daniel, Dhalla, Noreen, Dhir, Rajiv, Dookran, Sheliann S., Dresdner, Gideon, Eldridge, Jonathan, Eley, Greg, El-Naggar, Adel K., Eng, Stephanie, Fagin, James A., Fennell, Timothy, Ferris, Robert L., Fisher, Sheila, Frazer, Scott, Frick, Jessica, Gabriel, Stacey B., Ganly, Ian, Gao, Jianjiong, Garraway, Levi A., Gastier-Foster, Julie M., Getz, Gad, Gehlenborg, Nils, Ghossein, Ronald, Gibbs, Richard A., Giordano, Thomas J., Gomez-Hernandez, Karen, Grimsby, Jonna, Gross, Benjamin, Guin, Ranabir, Hadjipanayis, Angela, Harper, Hollie A., Hayes, D. Neil, Heiman, David I., Herman, James G., Hoadley, Katherine A., Hofree, Matan, Holt, Robert A., Hoyle, Alan P., Huang, Franklin W., Huang, Mei, Hutter, Carolyn M., Ideker, Trey, Iype, Lisa, Jacobsen, Anders, Jefferys, Stuart R., Jones, Corbin D., Jones, Steven J.M., Kasaian, Katayoon, Kebebew, Electron, Khuri, Fadlo R., Kim, Jaegil, Kramer, Roger, Kreisberg, Richard, Kucherlapati, Raju, Kwiatkowski, David J., Ladanyi, Marc, Lai, Phillip H., Laird, Peter W., Lander, Eric, Lawrence, Michael S., Lee, Darlene, Lee, Eunjung, Lee, Semin, Lee, William, Leraas, Kristen M., Lichtenberg, Tara M., Lichtenstein, Lee, Lin, Pei, Ling, Shiyun, Liu, Jinze, Liu, Wenbin, Liu, Yingchun, LiVolsi, Virginia A., Lu, Yiling, Ma, Yussanne, Mahadeshwar, Harshad S., Marra, Marco A., Mayo, Michael, McFadden, David G., Meng, Shaowu, Meyerson, Matthew, Mieczkowski, Piotr A., Miller, Michael, Mills, Gordon, Moore, Richard A., Mose, Lisle E., Mungall, Andrew J., Murray, Bradley A., Nikiforov, Yuri E., Noble, Michael S., Ojesina, Akinyemi I., Owonikoko, Taofeek K., Ozenberger, Bradley A., Pantazi, Angeliki, Parfenov, Michael, Park, Peter J., Parker, Joel S., Paull, Evan O., Pedamallu, Chandra Sekhar, Perou, Charles M., Prins, Jan F., Protopopov, Alexei, Ramalingam, Suresh S., Ramirez, Nilsa C., Ramirez, Ricardo, Raphael, Benjamin J., Rathmell, W. Kimryn, Ren, Xiaojia, Reynolds, Sheila M., Rheinbay, Esther, Ringel, Matthew D., Rivera, Michael, Roach, Jeffrey, Robertson, A. Gordon, Rosenberg, Mara W., Rosenthall, Matthew, Sadeghi, Sara, Saksena, Gordon, Sander, Chris, Santoso, Netty, Schein, Jacqueline E., Schultz, Nikolaus, Schumacher, Steven E., Seethala, Raja R., Seidman, Jonathan, Senbabaoglu, Yasin, Seth, Sahil, Sharpe, Samantha, Mills Shaw, Kenna R., Shen, John P., Shen, Ronglai, Sherman, Steven, Sheth, Margi, Shi, Yan, Shmulevich, Ilya, Sica, Gabriel L., Simons, Janae V., Sipahimalani, Payal, Smallridge, Robert C., Sofia, Heidi J., Soloway, Matthew G., Song, Xingzhi, Sougnez, Carrie, Stewart, Chip, Stojanov, Petar, Stuart, Joshua M., Tabak, Barbara, Tam, Angela, Tan, Donghui, Tang, Jiabin, Tarnuzzer, Roy, Taylor, Barry S., Thiessen, Nina, Thorne, Leigh, Thorsson, Vésteinn, Tuttle, R. Michael, Umbricht, Christopher B., Van Den Berg, David J., Vandin, Fabio, Veluvolu, Umadevi, Verhaak, Roel G.W., Vinco, Michelle, Voet, Doug, Walter, Vonn, Wang, Zhining, Waring, Scot, Weinberger, Paul M., Weinstein, John N., Weisenberger, Daniel J., Wheeler, David, Wilkerson, Matthew D., Wilson, Jocelyn, Williams, Michelle, Winer, Daniel A., Wise, Lisa, Wu, Junyuan, Xi, Liu, Xu, Andrew W., Yang, Liming, Yang, Lixing, Zack, Travis I., Zeiger, Martha A., Zeng, Dong, Zenklusen, Jean Claude, Zhao, Ni, Zhang, Hailei, Zhang, Jianhua, Zhang, Jiashan (Julia), Zhang, Wei, Zmuda, Erik, Zou., Lihua
Publicat a Cell (2014)