An immunosuppressive dendritic cell subset accumulates at secondary sites and promotes metastasis in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) after complete surgical resection is often followed by distant metastatic relapse for reasons that remain unclear. In this study, we investigated how the immune response at secondary sites affects tumor spread in murine models of metastatic PDAC. Early metasta...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kenkel, Justin A., Tseng, William W., Davidson, Matthew G., Tolentino, Lorna L., Choi, Okmi, Bhattacharya, Nupur, Seeley, E. Scott, Winer, Daniel A., Reticker-Flynn, Nathan E., Engleman, Edgar G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550516/
https://ncbi.nlm.nih.gov/pubmed/28611041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2212
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