A distinct subset of plasmacytoid dendritic cells induces activation and differentiation of B and T lymphocytes

Plasmacytoid dendritic cells (pDCs) are known mainly for their secretion of type I IFN upon viral encounter. We describe a CD2(hi)CD5(+)CD81(+) pDC subset, distinguished by prominent dendrites and a mature phenotype, in human blood, bone marrow, and tonsil, which can be generated from CD34(+) progen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Hong, Gregorio, Josh D., Iwahori, Toru, Zhang, Xiangyue, Choi, Okmi, Tolentino, Lorna L., Prestwood, Tyler, Carmi, Yaron, Engleman, Edgar G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338447/
https://ncbi.nlm.nih.gov/pubmed/28167780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610630114
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