CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions

Plasmacytoid dendritic cells (pDCs) are key regulators of anti-viral immunity. They rapidly secrete IFN-α and cross-present viral antigens thereby launching adaptive immunity. Here we show that activated human pDCs inhibit replication of cancer cells, and kill them in a contact dependent fashion. Ex...

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Detalhes bibliográficos
Main Authors: Matsui, Toshimichi, Connolly, John E., Michnevitz, Mark, Chaussabel, Damien, Yu, Chun-I, Glaser, Casey, Tindle, Sasha, Pypaert, Marc, Freitas, Heidi, Piqueras, Bernard, Banchereau, Jacques, Palucka, A. Karolina
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749454/
https://ncbi.nlm.nih.gov/pubmed/19454677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802008
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