B-1a Lymphocytes Attenuate Insulin Resistance

Obesity-associated insulin resistance, a common precursor of type 2 diabetes, is characterized by chronic inflammation of tissues, including visceral adipose tissue (VAT). Here we show that B-1a cells, a subpopulation of B lymphocytes, are novel and important regulators of this process. B-1a cells a...

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Bibliographic Details
Published in:Diabetes
Main Authors: Shen, Lei, Chng, MH, Alonso, Michael N., Yuan, Robert, Winer, Daniel A., Engleman, Edgar G.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2015
Subjects:
Immunology and Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303967/
https://ncbi.nlm.nih.gov/pubmed/25249575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0554
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