Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

During obesity, macrophages can infiltrate metabolic tissues, and contribute to chronic low-grade inflammation, and mediate insulin resistance and diabetes. Recent studies have elucidated the metabolic role of JAK2, a key mediator downstream of various cytokines and growth factors. Our study address...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Desai, Harsh R., Sivasubramaniyam, Tharini, Revelo, Xavier S., Schroer, Stephanie A., Luk, Cynthia T., Rikkala, Prashanth R., Metherel, Adam H., Dodington, David W., Park, Yoo Jin, Kim, Min Jeong, Rapps, Joshua A., Besla, Rickvinder, Robbins, Clinton S., Wagner, Kay-Uwe, Bazinet, Richard P., Winer, Daniel A., Woo, Minna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550513/
https://ncbi.nlm.nih.gov/pubmed/28794431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07923-0
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