Hepatic JAK2 protects against atherosclerosis through circulating IGF-1

Atherosclerosis is considered both a metabolic and inflammatory disease; however, the specific tissue and signaling molecules that instigate and propagate this disease remain unclear. The liver is a central site of inflammation and lipid metabolism that is critical for atherosclerosis, and JAK2 is a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:JCI Insight
Κύριοι συγγραφείς: Sivasubramaniyam, Tharini, Schroer, Stephanie A., Li, Angela, Luk, Cynthia T., Shi, Sally Yu, Besla, Rickvinder, Dodington, David W., Metherel, Adam H., Kitson, Alex P., Brunt, Jara J., Lopes, Joshua, Wagner, Kay-Uwe, Bazinet, Richard P., Bendeck, Michelle P., Robbins, Clinton S., Woo, Minna
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2017
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518558/
https://ncbi.nlm.nih.gov/pubmed/28724798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93735
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