Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in α-Synuclein Models of Parkinson's and Lewy Body Diseases

Por Spencer, Brian, Potkar, Rewati, Trejo, Margarita, Rockenstein, Edward, Patrick, Christina, Gindi, Ryan, Adame, Anthony, Wyss-Coray, Tony, Masliah, Eliezer
Publicado em 2009

Biochemical Properties of Highly Neuroinvasive Prion Strains

Por Bett, Cyrus, Joshi-Barr, Shivanjali, Lucero, Melanie, Trejo, Margarita, Liberski, Pawel, Kelly, Jeffery W., Masliah, Eliezer, Sigurdson, Christina J.
Publicado em 2012

Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson’s disease by disturbing calcium flux

Por Marongiu, Roberta, Spencer, Brian, Crews, Leslie, Adame, Anthony, Patrick, Christina, Trejo, Margarita, Dallapiccola, Bruno, Valente, Enza Maria, Masliah, Eliezer
Publicado em 2009

Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD

Por Nuber, Silke, Tadros, Daniel, Fields, Jerel, Overk, Cassia Rose, Ettle, Benjamin, Kosberg, Kori, Mante, Michael, Rockenstein, Edward, Trejo, Margarita, Masliah, Eliezer
Publicado no Acta Neuropathol (2014)

Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin

Por Ubhi, Kiren, Rockenstein, Edward, Doppler, Edith, Mante, Michael, Adame, Anthony, Patrick, Christina, Trejo, Margarita, Crews, Leslie, Paulino, Amy, Moessler, Herbert, Masliah, Eliezer
Publicado em 2009

Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure

Por Rockenstein, Edward, Ubhi, Kiren, Trejo, Margarita, Mante, Michael, Patrick, Christina, Adame, Anthony, Novak, Philipp, Jech, Marion, Doppler, Edith, Moessler, Herbert, Masliah, Eliezer
Publicado em 2014

Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy

Por Kim, Changyoun, Rockenstein, Edward, Spencer, Brian, Kim, Hyung-Koo, Adame, Anthony, Trejo, Margarita, Stafa, Klodjan, Lee, He-Jin, Lee, Seung-Jae, Masliah, Eliezer
Publicado no Cell Rep (2015)

The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons

Por Avdoshina, Valeria, Fields, Jerel Adam, Castellano, Paul, Dedoni, Simona, Palchik, Guillermo, Trejo, Margarita, Adame, Anthony, Rockenstein, Edward, Eugenin, Eliseo, Masliah, Eliezer, Mocchetti, Italo
Publicado no Neurotox Res (2016)

Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein

Por Games, Dora, Seubert, Peter, Rockenstein, Edward, Patrick, Christina, Trejo, Margarita, Ubhi, Kiren, Ettle, Benjamin, Ghassemiam, Majid, Barbour, Robin, Schenk, Dale, Nuber, Silke, Masliah, Eliezer
Publicado em 2013

HIV-1 Tat Alters Neuronal Autophagy by Modulating Autophagosome Fusion to the Lysosome: Implications for HIV-Associated Neurocognitive Disorders

Por Fields, Jerel, Dumaop, Wilmar, Elueteri, Simona, Campos, Sofia, Serger, Elisabeth, Trejo, Margarita, Kosberg, Kori, Adame, Anthony, Spencer, Brian, Rockenstein, Edward, He, Johnny J., Masliah, Eliezer
Publicado no J Neurosci (2015)

Blocking Aβ seeding-mediated aggregation and toxicity in an animal model of Alzheimer's Disease: A novel therapeutic strategy for neurodegeneration

Por Eleuteri, Simona, Di Giovanni, Saviana, Rockenstein, Edward, Mante, Mike, Adame, Antony, Trejo, Margarita, Wrasidlo, Wolf, Wu, Fang, Fraering, Patrick C., Masliah, Eliezer, Lashuel, Hilal A.
Publicado no Neurobiol Dis (2014)

Molecular determinants of α–synuclein mutants’ oligomerization and membrane interactions

Por Tsigelny, Igor F., Sharikov, Yuriy, Kouznetsova, Valentina L., Greenberg, Jerry P., Wrasidlo, Wolf, Overk, Cassia, Gonzalez, Tania, Trejo, Margarita, Spencer, Brian, Kosberg, Kori, Masliah, Eliezer
Publicado no ACS Chem Neurosci (2015)

Alzheimer brain-derived Aβ impairs synaptic remodelling and memory consolidation

Por Borlikova, Gilyana G., Trejo, Margarita, Mably, Alexandra J., Mc Donald, Jessica M., Frigerio, Carlo Sala, Regan, Ciaran M., Murphy, Keith J., Masliah, Eliezer, Walsh, Dominic M.
Publicado em 2012

Defining the Conformational Features of Anchorless, Poorly Neuroinvasive Prions

Por Bett, Cyrus, Kurt, Tim D., Lucero, Melanie, Trejo, Margarita, Rozemuller, Annemieke J., Kong, Qingzhong, Nilsson, K. Peter R., Masliah, Eliezer, Oldstone, Michael B., Sigurdson, Christina J.
Publicado em 2013

De Novo Prion Aggregates Trigger Autophagy in Skeletal Muscle

Por Joshi-Barr, Shivanjali, Bett, Cyrus, Chiang, Wei-Chieh, Trejo, Margarita, Goebel, Hans H., Sikorska, Beata, Liberski, Pawel, Raeber, Alex, Lin, Jonathan H., Masliah, Eliezer, Sigurdson, Christina J.
Publicado em 2014

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

Por Tsigelny, Igor F., Crews, Leslie, Desplats, Paula, Shaked, Gideon M., Sharikov, Yuriy, Mizuno, Hideya, Spencer, Brian, Rockenstein, Edward, Trejo, Margarita, Platoshyn, Oleksandr, Yuan, Jason X.-J., Masliah, Eliezer
Publicado em 2008

Proteomic Analysis of Highly Prevalent Amyloid A Amyloidosis Endemic to Endangered Island Foxes

Por Gaffney, Patricia M., Imai, Denise M., Clifford, Deana L., Ghassemian, Majid, Sasik, Roman, Chang, Aaron N., O’Brien, Timothy D., Coppinger, Judith, Trejo, Margarita, Masliah, Eliezer, Munson, Linda, Sigurdson, Christina
Publicado no PLoS One (2014)

Systemic AA amyloidosis in island foxes (Urocyon littoralis): Severity and risk factors

Por Gaffney, Patricia M., Witte, Carmel, Clifford, Deana L., Imai, Denise M., O’Brien, Timothy D., Trejo, Margarita, Liberta, Falk, Annamalai, Karthikeyan, Fändrich, Marcus, Masliah, Eliezer, Munson, Linda, Sigurdson, Christina J.
Publicado no Vet Pathol (2015)

HIV-1 Tat Activates Neuronal Ryanodine Receptors with Rapid Induction of the Unfolded Protein Response and Mitochondrial Hyperpolarization

Por Norman, John P., Perry, Seth W., Reynolds, Holly M., Kiebala, Michelle, De Mesy Bentley, Karen L., Trejo, Margarita, Volsky, David J., Maggirwar, Sanjay B., Dewhurst, Stephen, Masliah, Eliezer, Gelbard, Harris A.
Publicado em 2008

HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-Associated Neurocognitive Disorders

Por Fields, Jerel Adam, Serger, Elisabeth, Campos, Sofia, Divakaruni, Ajit S., Kim, Changyoun, Smith, Kendall, Trejo, Margarita, Adame, Anthony, Spencer, Brian, Rockenstein, Edward, Murphy, Anne N., Ellis, Ronald J., Letendre, Scott, Grant, Igor, Masliah, Eliezer
Publicado no Neurobiol Dis (2015)