HIV-1 Tat Alters Neuronal Autophagy by Modulating Autophagosome Fusion to the Lysosome: Implications for HIV-Associated Neurocognitive Disorders

Antiretroviral therapy has increased the life span of HIV+ individuals; however, HIV-associated neurocognitive disorder (HAND) occurrence is increasing in aging HIV patients. Previous studies suggest HIV infection alters autophagy function in the aging CNS and HIV-1 proteins affect autophagy in mono...

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Publicado en:J Neurosci
Autores principales: Fields, Jerel, Dumaop, Wilmar, Elueteri, Simona, Campos, Sofia, Serger, Elisabeth, Trejo, Margarita, Kosberg, Kori, Adame, Anthony, Spencer, Brian, Rockenstein, Edward, He, Johnny J., Masliah, Eliezer
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315828/
https://ncbi.nlm.nih.gov/pubmed/25653352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3207-14.2015
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