The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain

Por Mc Donald, Jessica M., Cairns, Nigel J., Taylor-Reinwald, Lisa, Holtzman, David, Walsh, Dominic M.
Publicado em 2012

Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice

Por Mably, Alexandra J., Liu, Wen, Mc Donald, Jessica M., Dodart, Jean-Cosme, Bard, Frédérique, Lemere, Cynthia A., O’Nuallain, Brian, Walsh, Dominic M.
Publicado no Neurobiol Dis (2015)

The presence of sodium dodecyl sulphate-stable Aβ dimers is strongly associated with Alzheimer-type dementia

Por Mc Donald, Jessica M., Savva, George M., Brayne, Carol, Welzel, Alfred T., Forster, Gill, Shankar, Ganesh M., Selkoe, Dennis J., Ince, Paul G., Walsh, Dominic M.
Publicado em 2010

The aqueous phase of Alzheimer’s disease brain contains assemblies built from ~4 and ~7 kDa Aβ species

Por Mc Donald, Jessica M., O’Malley, Tiernan T., Liu, Wen, Mably, Alexandra J., Brinkmalm, Gunnar, Portelius, Erik, Wittbold, William M., Frosch, Matthew P., Walsh, Dominic M.
Publicado no Alzheimers Dement (2015)

Alzheimer brain-derived Aβ impairs synaptic remodelling and memory consolidation

Por Borlikova, Gilyana G., Trejo, Margarita, Mably, Alexandra J., Mc Donald, Jessica M., Frigerio, Carlo Sala, Regan, Ciaran M., Murphy, Keith J., Masliah, Eliezer, Walsh, Dominic M.
Publicado em 2012

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

Por Kumar, Sathish, Rezaei-Ghaleh, Nasrollah, Terwel, Dick, Thal, Dietmar R, Richard, Mélisande, Hoch, Michael, Mc Donald, Jessica M, Wüllner, Ullrich, Glebov, Konstantin, Heneka, Michael T, Walsh, Dominic M, Zweckstetter, Markus, Walter, Jochen
Publicado em 2011

A Monoclonal Antibody Against Synthetic Aβ Dimer Assemblies Neutralizes Brain-Derived Synaptic Plasticity-Disrupting Aβ

Por O'Nuallain, Brian, Klyubin, Igor, Mc Donald, Jessica M., Foster, James S., Welzel, Alfred, Barry, Andrew, Dykoski, Richard K., Cleary, James P., Gebbink, Martijn F.B.G., Rowan, Michael J., Walsh, Dominic M.
Publicado em 2011

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

Por Freir, Darragh B., Nicoll, Andrew J., Klyubin, Igor, Panico, Silvia, Mc Donald, Jessica M., Risse, Emmanuel, Asante, Emmanuel A., Farrow, Mark A., Sessions, Richard B., Saibil, Helen R., Clarke, Anthony R., Rowan, Michael J., Walsh, Dominic M., Collinge, John
Publicado em 2011