Silk fibroin safety in the eye: a review that highlights a concern

Por Madden, Peter W, Klyubin, Igor, Ahearne, Mark J
Publicado no BMJ Open Ophthalmol (2020)

Synaptic plasticity in animal models of early Alzheimer's disease.

Por Rowan, Michael J, Klyubin, Igor, Cullen, William K, Anwyl, Roger
Publicado em 2003

GluN2B subunit-containing NMDA receptor antagonists prevent Aβ-mediated synaptic plasticity disruption in vivo

Por Hu, Neng-Wei, Klyubin, Igor, Anwyl, Roger, Rowan, Michael J.
Publicado em 2009

Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory

Por Klyubin, Igor, Cullen, William K, Hu, Neng-Wei, Rowan, Michael J
Publicado em 2012

Pre-plaque Aß-Mediated Impairment of Synaptic Depotentiation in a Transgenic Rat Model of Alzheimer’s Disease Amyloidosis

Por Qi, Yingjie, Klyubin, Igor, Hu, Neng-Wei, Ondrejcak, Tomas, Rowan, Michael J.
Publicado no Front Neurosci (2019)

Inherent Anti-amyloidogenic Activity of Human Immunoglobulin γ Heavy Chains

Por Adekar, Sharad P., Klyubin, Igor, Macy, Sally, Rowan, Michael J., Solomon, Alan, Dessain, Scott K., O'Nuallain, Brian
Publicado em 2010

Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo

Por Klyubin, Igor, Ondrejcak, Tomas, Hayes, Jennifer, Cullen, William K., Mably, Alexandra J., Walsh, Dominic M., Rowan, Michael J.
Publicado em 2014

Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer’s Disease Disrupt Synaptic Plasticity

Por Hu, Neng-Wei, Corbett, Grant T., Moore, Steven, Klyubin, Igor, O’Malley, Tiernan T., Walsh, Dominic M., Livesey, Frederick J., Rowan, Michael J.
Publicado no Cell Rep (2018)

Alzheimer's Disease Brain-Derived Amyloid-β-Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein

Por Barry, Andrew E., Klyubin, Igor, Mc Donald, Jessica M., Mably, Alexandra J., Farrell, Michael A., Scott, Michael, Walsh, Dominic M., Rowan, Michael J.
Publicado no J Neurosci (2011)

Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo

Por Ondrejcak, Tomas, Klyubin, Igor, Corbett, Grant T., Fraser, Graham, Hong, Wei, Mably, Alexandra J., Gardener, Matthew, Hammersley, Jayne, Perkinton, Michael S., Billinton, Andrew, Walsh, Dominic M., Rowan, Michael J.
Publicado no J Neurosci (2018)

Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms

Por Harte, Níal P., Klyubin, Igor, McCarthy, Eoin K., Min, Soyoung, Garrahy, Sarah Ann, Xie, Yongjing, Davey, Gavin P., Boland, John J., Rowan, Michael J., Mok, K. Hun
Publicado no J Biol Chem (2015)

Secreted Amyloid β-Proteins in a Cell Culture Model Include N-Terminally Extended Peptides That Impair Synaptic Plasticity

Por Welzel, Alfred T., Maggio, John E., Shankar, Ganesh M., Walker, Donald E., Ostaszewski, Beth L., Li, Shaomin, Klyubin, Igor, Rowan, Michael J., Seubert, Peter, Walsh, Dominic M., Selkoe, Dennis J.
Publicado em 2014

Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity

Por Klyubin, Igor, Nicoll, Andrew J., Khalili-Shirazi, Azadeh, Farmer, Michael, Canning, Stephanie, Mably, Alexandra, Linehan, Jacqueline, Brown, Alexander, Wakeling, Madeleine, Brandner, Sebastian, Walsh, Dominic M., Rowan, Michael J., Collinge, John
Publicado em 2014

A Monoclonal Antibody Against Synthetic Aβ Dimer Assemblies Neutralizes Brain-Derived Synaptic Plasticity-Disrupting Aβ

Por O'Nuallain, Brian, Klyubin, Igor, Mc Donald, Jessica M., Foster, James S., Welzel, Alfred, Barry, Andrew, Dykoski, Richard K., Cleary, James P., Gebbink, Martijn F.B.G., Rowan, Michael J., Walsh, Dominic M.
Publicado em 2011

Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization

Por Klyubin, Igor, Betts, Vicki, Welzel, Alfred T., Blennow, Kaj, Zetterberg, Henrik, Wallin, Anders, Lemere, Cynthia A., Cullen, William K., Peng, Ying, Wisniewski, Thomas, Selkoe, Dennis J., Anwyl, Roger, Walsh, Dominic M., Rowan, Michael J.
Publicado em 2008

Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human Aß-induced synaptic dysfunction in individual freely behaving pre-plaque transg...

Por Qi, Yingjie, Klyubin, Igor, Harney, Sarah C, Hu, NengWei, Cullen, William K, Grant, Marianne K, Steffen, Julia, Wilson, Edward N, Do Carmo, Sonia, Remy, Stefan, Fuhrmann, Martin, Ashe, Karen H, Cuello, A Claudio, Rowan, Michael J
Publicado no Acta Neuropathol Commun (2014)

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

Por Freir, Darragh B., Nicoll, Andrew J., Klyubin, Igor, Panico, Silvia, Mc Donald, Jessica M., Risse, Emmanuel, Asante, Emmanuel A., Farrow, Mark A., Sessions, Richard B., Saibil, Helen R., Clarke, Anthony R., Rowan, Michael J., Walsh, Dominic M., Collinge, John
Publicado em 2011

Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo

Por An, Kyongman, Klyubin, Igor, Kim, Youngkyu, Jung, Jung Hoon, Mably, Alexandra J, O’Dowd, Sean T, Lynch, Timothy, Kanmert, Daniel, Lemere, Cynthia A, Finan, Gina M, Park, Joon Won, Kim, Tae-Wan, Walsh, Dominic M, Rowan, Michael J, Kim, Joung-Hun
Publicado no Mol Brain (2013)