Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo

Intracellular neurofibrillary tangles (NFTs) composed of tau protein are a neuropathological hallmark of several neurodegenerative diseases, the most common of which is Alzheimer's disease (AD). For some time NFTs were considered the primary cause of synaptic dysfunction and neuronal death, how...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Neurosci
Main Authors: Ondrejcak, Tomas, Klyubin, Igor, Corbett, Grant T., Fraser, Graham, Hong, Wei, Mably, Alexandra J., Gardener, Matthew, Hammersley, Jayne, Perkinton, Michael S., Billinton, Andrew, Walsh, Dominic M., Rowan, Michael J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2018
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290298/
https://ncbi.nlm.nih.gov/pubmed/30355631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1700-18.2018
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