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Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo

Many endogenous factors influence the time course and extent of the detrimental effects of amyloid β-protein (Aβ) on synaptic function. Here, we assessed the impact of varying endogenous glutamatergic and cholinergic transmission by pharmacological means on the disruption of plasticity at hippocampa...

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Detalhes bibliográficos
Main Authors: Klyubin, Igor, Ondrejcak, Tomas, Hayes, Jennifer, Cullen, William K., Mably, Alexandra J., Walsh, Dominic M., Rowan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843879/
https://ncbi.nlm.nih.gov/pubmed/24298149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0147
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