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Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory

Alzheimer’s disease (AD) is characterized by episodic memory impairment that often precedes clinical diagnosis by many years. Probing the mechanisms of such impairment may provide much needed means of diagnosis and therapeutic intervention at an early, pre-dementia, stage. Prior to the onset of sign...

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Detalhes bibliográficos
Main Authors: Klyubin, Igor, Cullen, William K, Hu, Neng-Wei, Rowan, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502131/
https://ncbi.nlm.nih.gov/pubmed/22805374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-25
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