Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization

The current development of immunotherapy for Alzheimer's disease is based on the assumption that human-derived amyloid β protein (Aβ) can be targeted in a similar manner to animal cell-derived or synthetic Aβ. Because the structure of Aβ depends on its source and the presence of cofactors, it i...

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Detalhes bibliográficos
Main Authors: Klyubin, Igor, Betts, Vicki, Welzel, Alfred T., Blennow, Kaj, Zetterberg, Henrik, Wallin, Anders, Lemere, Cynthia A., Cullen, William K., Peng, Ying, Wisniewski, Thomas, Selkoe, Dennis J., Anwyl, Roger, Walsh, Dominic M., Rowan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685151/
https://ncbi.nlm.nih.gov/pubmed/18417702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5161-07.2008
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