Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer’s brain

The primary structure of canonical amyloid-β-protein was elucidated more than 30 years ago, yet the forms of amyloid-β that play a role in Alzheimer’s disease pathogenesis remain poorly defined. Studies of Alzheimer’s disease brain extracts suggest that amyloid-β, which migrates on sodium dodecyl su...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Brinkmalm, Gunnar, Hong, Wei, Wang, Zemin, Liu, Wen, O’Malley, Tiernan T, Sun, Xin, Frosch, Matthew P, Selkoe, Dennis J, Portelius, Erik, Zetterberg, Henrik, Blennow, Kaj, Walsh, Dominic M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487330/
https://ncbi.nlm.nih.gov/pubmed/31032851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz066
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