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Biomarkers in Amyloid-β Immunotherapy Trials in Alzheimer's Disease

Drug candidates directed against amyloid-β (Aβ) are mainstream in Alzheimer's disease (AD) drug development. Active and passive Aβ immunotherapy is the principle that has come furthest, both in number and in stage of clinical trials. However, an increasing number of reports on major difficultie...

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Detalhes bibliográficos
Main Authors: Blennow, Kaj, Hampel, Harald, Zetterberg, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857643/
https://ncbi.nlm.nih.gov/pubmed/23799530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.154
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