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Biomarkers in Amyloid-β Immunotherapy Trials in Alzheimer's Disease

Drug candidates directed against amyloid-β (Aβ) are mainstream in Alzheimer's disease (AD) drug development. Active and passive Aβ immunotherapy is the principle that has come furthest, both in number and in stage of clinical trials. However, an increasing number of reports on major difficultie...

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Hlavní autoři: Blennow, Kaj, Hampel, Harald, Zetterberg, Henrik
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857643/
https://ncbi.nlm.nih.gov/pubmed/23799530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.154
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