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Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson’s disease by disturbing calcium flux
Parkinson’s disease (PD) is characterized by accumulation of α-synuclein and degeneration of neuronal populations in cortical and subcortical regions. Mitochondrial dysfunction has been considered a potential unifying factor in the pathogenesis of the disease. Mutations in genes linked to familial f...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902824/ https://ncbi.nlm.nih.gov/pubmed/19166511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05932.x |
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