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Statins reduce neuronal α-synuclein aggregation in in vitro models of Parkinson's disease

Aggregation of α-synuclein (α-syn) is believed to play a critical role in the pathogenesis of disorders such as dementia with Lewy bodies and Parkinson’s disease. The function of α-syn remains unclear, although several lines of evidence suggest that α-syn is involved in synaptic vesicle trafficking...

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Detalhes bibliográficos
Main Authors: Bar-On, Pazit, Crews, Leslie, Koob, Andrew O., Mizuno, Hideya, Adame, Anthony, Spencer, Brian, Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822545/
https://ncbi.nlm.nih.gov/pubmed/18248604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05254.x
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