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α-Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice

Altered expression and mutations in α-synuclein (α-syn) have been linked to Parkinson's disease (PD) and related disorders. The neurological alterations in PD patients have been associated with degeneration of dopaminergic cells and other neuronal populations. Moreover, recent studies in murine...

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Bibliografiske detaljer
Main Authors: Crews, Leslie, Mizuno, Hideya, Desplats, Paula, Rockenstein, Edward, Adame, Anthony, Patrick, Christina, Winner, Beate, Winkler, Juergen, Masliah, Eliezer
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666311/
https://ncbi.nlm.nih.gov/pubmed/18417705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0066-08.2008
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