α-Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice

Altered expression and mutations in α-synuclein (α-syn) have been linked to Parkinson's disease (PD) and related disorders. The neurological alterations in PD patients have been associated with degeneration of dopaminergic cells and other neuronal populations. Moreover, recent studies in murine...

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Autors principals: Crews, Leslie, Mizuno, Hideya, Desplats, Paula, Rockenstein, Edward, Adame, Anthony, Patrick, Christina, Winner, Beate, Winkler, Juergen, Masliah, Eliezer
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666311/
https://ncbi.nlm.nih.gov/pubmed/18417705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0066-08.2008
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