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The Temporal Expression Pattern of Alpha-Synuclein Modulates Olfactory Neurogenesis in Transgenic Mice

BACKGROUND: Adult neurogenesis mirrors the brain´s endogenous capacity to generate new neurons throughout life. In the subventricular zone/ olfactory bulb system adult neurogenesis is linked to physiological olfactory function and has been shown to be impaired in murine models of neuronal alpha-Synu...

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Bibliographic Details
Published in:PLoS One
Main Authors: Schreglmann, Sebastian R., Regensburger, Martin, Rockenstein, Edward, Masliah, Eliezer, Xiang, Wei, Winkler, Jürgen, Winner, Beate
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427489/
https://ncbi.nlm.nih.gov/pubmed/25961568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126261
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